St. Joseph, Missouri - Was well known to early river travelers and was called St. Michael’s Prairie. On July 7,1804 Lewis and Clark documented in their journal the flora & fauna in the St. Michael’s Prairie. St. Joseph is also home of outlaw Jesse James.
Regional POI Map

Nebraska City, Nebraska – Missouri River Basin Lewis and Clark Interpretive Center.  The focus of this exciting regional Missouri River Basin Lewis and Clark Interpretive Center is on the more than 300 discoveries of flora (178 plants), fauna (122 animals) and scientific discoveries made at President Thomas Jefferson's direction. 
Timeline & Map PDF  720 KB

Bellevue, Nebraska - National Children's Lewis and Clark Interpretive Art Wall.  The Art Wall is built on the peninsula just south of the boat ramp in Haworth Park, Nebraska.  The artwork selected was from students in grades three through six in communities along the routes of the Lewis and Clark expedition.  Each piece of artwork was reproduced on weatherproof tiles for permanent display on a sculptural art wall.  Artwork is arranged geographically into seven regions, from Illinois to Oregon, interpreting the journey across the continent. 

Omaha, Nebraska - Durham Western Heritage Museum ( used to be known as Union Station.)   It was built by Union Pacific Railroad as a showpiece in the city of their headquarters in the classic art deco style.  In its heyday, 64 trains and 10,000 passengers passed through Union Station every day.

Council Bluffs, Iowa – Western Historic Trails Center.     On the banks of the Missouri River explore western history.